Active surveillance as a practical strategy to differentiate lethal and non-lethal prostate cancer subtypes
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چکیده
منابع مشابه
Active surveillance as a practical strategy to differentiate lethal and non-lethal prostate cancer subtypes.
Differentiation between lethal and non-lethal prostate cancer subtypes has become a very important issue in avoiding excessive treatment in an era when prostate-specific antigen (PSA) screening has reduced the rate of prostate cancer deaths by more than 20%. However, it is difficult to determine the patients who may or may not benefit from immediate treatment interventions at the time of the in...
متن کاملHelping to address the over treatment of prostate cancer: tools to differentiate lethal and non-lethal phenotype in prostate cancer.
011 was a noteworthy year for those interested in the care of patients with prostate cancer. First, the US Preventive Services Task Force (USPSTF) released an update on prostate cancer screening, and recommended against the use of the prostate-specific antigen (PSA) test for all men, regardless of family history or race. While this surprised many in the field, the conclusion that there is more ...
متن کاملDifferentiation of lethal and non lethal prostate cancer: PSA and PSA isoforms and kinetics.
Prostate-specific antigen (PSA) testing for the early diagnosis of prostate cancer has led to a decrease in cancer mortality. However, the high prevalence of low-grade prostate cancer and its long natural history, competing causes of death in older men and treatment patterns of prostate cancer, have led to dramatic overtreatment of the disease. Improved markers of prostate cancer lethality are ...
متن کاملProstate-specific antigen levels as a predictor of lethal prostate cancer.
BACKGROUND Rates of long-term survival among patients with untreated localized prostate cancer are high. To avoid unnecessary treatment, tools are needed to identify the small proportion of patients who are destined to develop lethal prostate cancer. METHODS To evaluate the accuracy of early changes in prostate-specific antigen (PSA) levels as predictors of prostate cancer outcome, we assesse...
متن کاملProstate cancer - active surveillance as a management option.
BACKGROUND Active surveillance, followed by delayed definitive treatment for those who develop evidence of significant cancer progression, is now a recognised management strategy for selected men with low risk prostate cancer. OBJECTIVE This article summarises the role of active surveillance in the management of prostate cancer. It outlines the benefits of active surveillance and the indicati...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2012
ISSN: 1008-682X,1745-7262
DOI: 10.1038/aja.2011.151